Second Opinion®- User Manual

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Second Opinion® applies bounding boxes around all potential pathologic and non-pathologic features that it detects. These bounding boxes are color coded according to the system’s confidence in a detection’s accuracy. Users should understand how Second Opinion® evaluates the accuracy of a detection in order to make informed use of its detection capabilities.

The system’s confidence is determined by the specificity of discernment required to make a detection.Detections that the system is most confident in are those made when a high specificity of discernment is required to flag a detection. Naturally, the system makes fewer detections when it approaches them with a high specificity requirement.

When the specificity requirement is relaxed, the system will make more detections, but it will be less confident in their accuracy. In other words, when specificity requirements are lowered ,the system will be more sensitive to the presence of potential pathologic and non-pathologic features in a radiograph, at the risk of flagging features that are not present (false positive detections).

In order to offer a comprehensive list of features potentially warranting the user’s attention, Second Opinion® is designed to approach the detection process with varying degrees of specificity.

The detections presented by the Second Opinion® Client are color coded to allow users to understand whether the detection is the product of a) a specificity-first detection approach, b) a sensitivity-first detection approach, or c) a detection approach that balances specificity and sensitivity.

Users should consider every Second Opinion® detection in light of the color of the bounding box inscribing it (or the color of the three dots next to the detected feature’s name in the Condition index). The detection color codes are as follows:

●    Aqua Blue:The system is highly confident in the detection’s accuracy.

●    Yellow: The system is moderately confident in the detection’s accuracy.

●    Red: The system has low confidence in the detection’s accuracy.

Second Opinion® users should move the Confidence Slider (found at the top of the Conditions index) between the red/low, yellow/medium, and aqua/high positions to gain a fuller understanding of the qualitative character of the Second Opinion® detections prior to taking any Second Opinion® detections into consideration.

With the slider on the"Low" setting, all three types of boxes (aqua, yellow, red) are displayed.

Explanation of the Confidence Slider functionality is included inSection 5.2.10 of this User Manual.