Second Opinion®
Smarter Radiology
Pearl sharpens your x-ray expertise with dental AI for faster, more accurate diagnoses and clearer, trusted patient conversations.
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Clinically Tested, Independently Validated
Pearl is the only dental imaging AI validated by an independent third party to be 94% accurate in detecting dental disease. From AI caries detection to bone loss and periapical findings, every layer of Pearl's AI is backed by peer-reviewed research and millions of real-world radiographs.
increase in monthly diagnoses1
more procedures diagnosed2
more periodontal diagnoses3
Earn patient trust with better presentations
Colorful highlights and tooth parts mapping help patients see and understand their diagnosis and how disease could affect their unique oral anatomy.
Patient-friendly tools include:
- Intuitive color-coding and clear decay metrics
- Tooth Parts mapping that shows how disease affects their anatomy
- Comparison mode to illustrate disease progression
- Patient health reports that remind them why they need care
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Eliminate guesswork with clear findings
See early and progressed decay, bone loss, and restorations highlighted and quantified automatically. Fast, accurate, and easy to review, Pearl's dental AI delivers findings automatically, inside the workflow you already use.
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Deliver your best care, everyday
Diagnose and treat with precision, even on your "off" days. Pearl's dental imaging AI analyzes each radiograph in 30 seconds or less, backed by research and more than 7 million verified cases. With dental AI catching what tired eyes miss, you make confident decisions faster — every patient, every chair, every shift.
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Powerful dental imaging AI for the platforms you know
Start using Second Opinion® directly within every major dental software—no disruptions or system overhauls.
Proven Impact
Read about how organizations of every size use Pearl to improve their operations and deliver better dentistry.
FAQ
What is Pearl Second Opinion® and how does it work?
Second Opinion® is Pearl’s FDA-cleared AI for real-time pathology detection on 2D dental X-rays. It integrates directly with your imaging system and automatically analyzes every bitewing, periapical, and panoramic radiograph as it’s captured, highlighting up to 18 findings per image — including caries, bone loss, calculus, periapical radiolucencies, defective margins, and existing restorations. Most images are processed in seconds, with 90%+ loading in under one minute, and detections appear right inside your existing imaging workflow.
How accurate is Pearl Second Opinion® at detecting cavities and other dental conditions?
Second Opinion® achieves over 95% accuracy in identifying dental conditions and is trained on the world’s largest dental radiograph dataset, annotated by world-renowned dentists and radiologists. In a published clinical study, operator diagnostic accuracy improved from 82% to 98% when supported by Pearl, and practices identify 37% more disease on average. Second Opinion® holds FDA clearances for both intraoral (bitewing, periapical) and extraoral (panoramic) radiographs, with continuous model updates.
What dental conditions can Second Opinion® detect on X-rays?
Second Opinion® detects up to 18 findings per image, including incipient and progressed caries, bone loss measured in millimeters and ratios, calculus, periapical radiolucencies, defective restoration margins, widened periodontal ligament, and impactions. It also identifies existing restorations — metal and non-metal crowns, fillings, bridges, root canals, and implants — and assesses tooth parts (enamel, dentin, pulp, cementum) to support crown planning, treatment planning, and patient case presentation.
Does Pearl Second Opinion® integrate with my dental imaging software?
Yes. Second Opinion® integrates natively with 40+ imaging and practice management systems, including DEXIS, Carestream, Romexis, Sidexis, Apteryx XVWeb, MiPACS, SOTA Cloud, Tab32, Open Dental, Eaglesoft, Curve, and Dentally. It’s also available as a standalone web app at secondopinion.hellopearl.com. If your imaging system can display X-rays, Pearl can integrate with it. Setup is typically completed within hours, and our team handles the technical integration end to end.
How does Second Opinion® improve patient case acceptance?
Practices using Second Opinion® report a 30% average lift in case acceptance, including +37% for scaling and root planing, +34% for crowns, +23% for root canals, +19% for fillings, +18% for implants, and +39% for restorative replacements. AI-generated color overlays, tooth-part mapping, side-by-side disease-progression views, and patient-friendly take-home reports help patients see and understand their condition — which builds trust and motivates them to move forward with treatment.